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Nutlin-C1-amido-PEG4-C2-N3

Product Specifications

Target

Others, E3 Ligase Ligand-Linker Conjugate

Related Pathways

Others, PROTAC

Bioactivity

Nutlin-C1-amido-PEG4-C2-N3 is a novel ligand-linker conjugate for the E3 ligase, incorporating the MDM2 ligand from Nutlin 3 and a 4-unit PEG linker. This compound is specifically designed for use in PROTAC technology.

Smiles

O=C(CN(C(N1C(C2=CC=C(OC)C=C2OC(C)C)=N[C@H](C3=CC=C(Cl)C=C3)[C@@H]1C4=CC=C(Cl)C=C4)=O)CC5)N5CC(NCCOCCOCCOCCOCCN=[N+]=[N-])=O

Molecular Formula

C42H52Cl2N8O9

Molecular Weight

883.82

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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