Tazemetostat
Product Specifications
CAS Number
1403254-99-8
Target
Apoptosis, Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic, Apoptosis
Purity
0.9984
Bioactivity
Tazemetostat (EPZ6438) is a histone methyltransferase EZH2 inhibitor (IC50=11 nM) that is orally active, selective, and SAM-competitive. Tazemetostat exhibits antitumor activity and may be used for the treatment of epithelioid sarcoma/follicular lymphoma.
Smiles
CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(CN2CCOCC2)cc1
Molecular Formula
C34H44N4O4
Molecular Weight
572.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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