Palbociclib
Product Specifications
CAS Number
571190-30-2
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.999
Bioactivity
Palbociclib (PD 0332991) is a CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16 nM) and is orally active. Palbociclib has anti-tumorigenic activity and has investigational potential for use in ER-positive and HER2-negative breast cancer.
Smiles
O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)N4CCNCC4)N2)C5CCCC5
Molecular Formula
C24H29N7O2
Molecular Weight
447.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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