Clovamide

Clovamide (trans-Clovamide), a natural phenolic compound, is a potent antioxidant. Clovamide is an excellent ROS and oxygen radical scavenger. Clovamide also has anti-inflammatory and neuroprotective effects[1][2]. Clovamide is an anti-microbial with activity against the human pathogens influenza A subtype H5N1, Trypanosoma evansi, and Heliobacter pylori[3].

Product Specifications

CAS Number

[53755-02-5]

Product Name Alternative

Trans-Clovamide

UNSPSC

12352005

Target

Apoptosis; Bacterial; Influenza Virus; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/clovamide.html

Purity

98.09

Solubility

DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC1=CC=C(C=C1O)/C=C/C(N[C@@H](CC2=CC=C(C(O)=C2)O)C(O)=O)=O

Molecular Formula

C18H17NO7

Molecular Weight

359.33

References & Citations

[1]Naike Ye, et al. Antioxidant studies by hydrodynamic voltammetry and DFT, quantitative analyses by HPLC-DAD of clovamide, a natural phenolic compound found in Theobroma Cacao L. beans. Food Chem. 2021 Mar 30;341 (Pt 2) :128260.|[2]S Fallarini, et al. Clovamide and rosmarinic acid induce neuroprotective effects in in vitro models of neuronal death. Br J Pharmacol. 2009 Jul;157 (6) :1072-84.