Canagliflozin
Product Specifications
CAS Number
842133-18-0
Target
SGLT
Related Pathways
GPCR/G Protein
Purity
>99.99%
Bioactivity
Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM) . Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM) .
Smiles
O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC=3SC(=CC3)C4=CC=C(F)C=C4)=C(C)C=C2
Molecular Formula
C24H25FO5S
Molecular Weight
444.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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