Canagliflozin

Product Specifications

CAS Number

842133-18-0

Target

SGLT

Related Pathways

GPCR/G Protein

Purity

>99.99%

Bioactivity

Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM) . Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM) .

Smiles

O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC=3SC(=CC3)C4=CC=C(F)C=C4)=C(C)C=C2

Molecular Formula

C24H25FO5S

Molecular Weight

444.52

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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