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DBCO-PEG4-VC-PAB-DMEA-PNU-159682

Product Specifications

CAS Number

2259318-56-2

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for antibody-drug conjugates (ADC), comprises the ADC linker DBCO-PEG4-VC-PAB and the potent ADC cytotoxin DMEA-PNU-159682, which includes metabolites of nemorubicin (MMDX) from liver microsomes and the ADC cytotoxin PNU-159682[1].

Smiles

O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4OC)C[C@](C(COC(N(CCN(C(OCC5=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCC(NCCC(=O)N6C=7C(C#CC=8C(C6)=CC=CC8)=CC=CC7)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C5)=O)C)C)=O)=O)(O)C1)[C@H]9C[C@@]%10(N%11[C@](O[C@@]%10([C@H](C)O9)[H])([C@@H](OC)OCC%11)[H])[H]

Molecular Formula

C86H106N10O26

Molecular Weight

1695.81

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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