SAG
Product Specifications
CAS Number
912545-86-9
Target
Hedgehog/Smoothened, Smo
Related Pathways
Stem Cells, GPCR/G Protein
Purity
0.9888
Bioactivity
SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.
Smiles
CN[C@H]1CC[C@@H](CC1)N(Cc1cccc(c1)-c1ccncc1)C(=O)c1sc2ccccc2c1Cl
Molecular Formula
C28H28ClN3OS
Molecular Weight
490.06
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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