Nintedanib
Product Specifications
CAS Number
656247-17-5
Target
PDGFR|||FLT|||VEGFR|||FGFR|||Src
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis
Purity
0.9992
Bioactivity
Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFR?, and PDGFR? (IC50=59/65 nM) . Nintedanib has antitumor activity and inhibits tumor growth by inhibiting angiogenesis.
Smiles
COC(c1cc2c(/C(C(N2)=O)=C(c3ccccc3)/Nc4ccc(N(C(CN5CCN(CC5)C)=O)C)cc4)cc1)=O
Molecular Formula
C31H33N5O4
Molecular Weight
539.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
126748-ML490 100 µL
FERMT1 (C20orf42, Kindlerin, Kindlin Syndrome Protein, Kindlin-1, Unc-112-related Protein 1, Fermitin Family Homolog 1, KIND1, URP1, FLJ20116, FLJ23423) (MaxLight 490)
Ask
View Details 
