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Afatinib Dimaleate

Product Specifications

CAS Number

850140-73-7

Target

Apoptosis|||p38 MAPK|||Akt|||c-Met/HGFR|||HER|||Autophagy|||EGFR

Related Pathways

Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Autophagy|||JAK/STAT signaling|||Cytoskeletal Signaling|||Apoptosis|||MAPK

Purity

>99.99%

Bioactivity

Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity.

Smiles

OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1

Molecular Formula

C32H33ClFN5O11

Molecular Weight

718.08

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/F58E72E9-0681-4EA3-9232-1803F07463CE/T1773

Available Sizes

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