Afatinib Dimaleate
Product Specifications
CAS Number
850140-73-7
Target
Apoptosis|||p38 MAPK|||Akt|||c-Met/HGFR|||HER|||Autophagy|||EGFR
Related Pathways
Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Autophagy|||JAK/STAT signaling|||Cytoskeletal Signaling|||Apoptosis|||MAPK
Purity
>99.99%
Bioactivity
Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity.
Smiles
OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1
Molecular Formula
C32H33ClFN5O11
Molecular Weight
718.08
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6464561-01 0.1 mL
Aurora C, NT (G11) (Aurora/IPL1/Eg2 Protein 2, Aurora/IPL1-related Kinase 3, Serine/Threonine Protein Kinase 13, Aurora-related Kinase 3, ARK-3, Aurora Kinase C, Serine/Threonine-protein Kinase Aurora-C, AURKC, AIE2, AIK3, ARK3, STK13) (MaxLight 750)
Ask
View Details MBS6464561-02 5x 0.1 mL
Aurora C, NT (G11) (Aurora/IPL1/Eg2 Protein 2, Aurora/IPL1-related Kinase 3, Serine/Threonine Protein Kinase 13, Aurora-related Kinase 3, ARK-3, Aurora Kinase C, Serine/Threonine-protein Kinase Aurora-C, AURKC, AIE2, AIK3, ARK3, STK13) (MaxLight 750)
Ask
View Details GTR15119759 1 Vial
Lentiviral human SLC25A53 shRNA (UAS) - Lentiviral human SLC25A53 shRNA (UAS, RFP) (25)
Ask
View Details MBS1433318-01 0.02 mg (E-Coli)
Recombinant Chromohalobacter salexigens Bifunctional protein HldE (hldE)
Ask
View Details