Afatinib Dimaleate

Product Specifications

CAS Number

850140-73-7

Target

Apoptosis|||p38 MAPK|||Akt|||c-Met/HGFR|||HER|||Autophagy|||EGFR

Related Pathways

Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Autophagy|||JAK/STAT signaling|||Cytoskeletal Signaling|||Apoptosis|||MAPK

Purity

>99.99%

Bioactivity

Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity.

Smiles

OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1

Molecular Formula

C32H33ClFN5O11

Molecular Weight

718.08

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

62046 1 PC

Guide Cannula-Double/O.D.0.64mm-23G/C.C2.4/B7.8/M5

Ask

View Details

EK246278 96 Well

Rat KLF2 (Kruppel Like Factor 2, Lung) ELISA Kit

Ask

View Details

HK208119 1 Kit

ZNF256 Human qPCR Template Standard (NM_005773)

Ask

View Details

GTR15376065 1 Vial

Lentiviral human PEX11G sgRNA gene knockout kit - Lentiviral human PEX11G sgRNA gene knockout kit (25)

Ask

View Details

123188 100 µg

ALB (Albumin, Serum Albumin, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341)

Ask

View Details

EMK0264 96 Tests

Monkey IL-33 (Interleukin-33) ELISA Kit

Ask

View Details