Afatinib Dimaleate
Product Specifications
CAS Number
850140-73-7
Target
Apoptosis, p38 MAPK, Akt, c-Met/HGFR, HER, Autophagy, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Angiogenesis, Autophagy, JAK/STAT signaling, Cytoskeletal Signaling, Apoptosis, MAPK
Purity
>99.99%
Bioactivity
Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity.
Smiles
OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1
Molecular Formula
C32H33ClFN5O11
Molecular Weight
718.08
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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