YK11

YK11 is a partial agonist of androgen receptor, with osteogenic activity.

Product Specifications

CAS Number

[1370003-76-1]

UNSPSC

12352005

Hazard Statement

H315, H317, H318, H334, H335, H341, H361, H370, H413

Target

Androgen Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/YK11.html

Purity

98.06

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

O=C1CCC2C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4(OC(C)(OC)O/5)C5=C/C(OC)=O)=C1

Molecular Formula

C25H34O6

Molecular Weight

430.53

Precautions

H315, H317, H318, H334, H335, H341, H361, H370, H413

References & Citations

[1]Kanno Y, et al. Selective androgen receptor modulator, YK11, regulates myogenic differentiation of C2C12 myoblasts by follistatin expression. Biol Pharm Bull. 2013;36 (9) :1460-5.|[2]Yatsu T, et al. Selective Androgen Receptor Modulator, YK11, Up-Regulates Osteoblastic Proliferation and Differentiation in MC3T3-E1 Cells. Biol Pharm Bull. 2018;41 (3) :394-398.