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8-iso Prostaglandin E1

8-iso Prostaglandin E1 (Ovinonic acid; 8-iso-PGE1) is a spasmodic agent in canine pulmonary veins and can also cause vasodilation[1].

Product Specifications

CAS Number

[21003-46-3]

Product Name Alternative

Ovinonic acid; 8-iso-PGE1

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/8-iso-prostaglandin-e1.html

Solubility

10 mM in DMSO

Smiles

OC(CCCCCC[C@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@@H](O)CCCCC)=O

Molecular Formula

C20H34O5

Molecular Weight

354.48

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Janssen LJ, et al. Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles. Br J Pharmacol. 2001 Jan;132 (1) :127-34.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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