8-iso Prostaglandin E1
8-iso Prostaglandin E1 (Ovinonic acid; 8-iso-PGE1) is a spasmodic agent in canine pulmonary veins and can also cause vasodilation[1].
Product Specifications
CAS Number
[21003-46-3]
Product Name Alternative
Ovinonic acid; 8-iso-PGE1
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/8-iso-prostaglandin-e1.html
Solubility
10 mM in DMSO
Smiles
OC(CCCCCC[C@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@@H](O)CCCCC)=O
Molecular Formula
C20H34O5
Molecular Weight
354.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Janssen LJ, et al. Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles. Br J Pharmacol. 2001 Jan;132 (1) :127-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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