Adezmapimod
Product Specifications
CAS Number
152121-47-6
Target
HSP, p38 MAPK, Mitophagy, Autophagy
Related Pathways
Cytoskeletal Signaling, Metabolism, Autophagy, MAPK
Purity
0.9993
Bioactivity
Adezmapimod (SB 203580) is a selective, ATP-competitive p38 MAPK inhibitor (IC50=0.3-0.5 μM) that activates autophagy and mitochondrial autophagy, with more than 100-fold higher selectivity over PKB, LCK, and GSK-3β.
Smiles
FC1=CC=C(C2=C(N=C(N2)C3=CC=C(S(C)=O)C=C3)C=4C=CN=CC4)C=C1
Molecular Formula
C21H16FN3OS
Molecular Weight
377.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
EK10F780-01 48 Test
Canine Angiopoietin 1 (ANGPT1) ELISA Kit-Sandwich
Sign In for Pricing
View Details EK10F780-02 96 Tests
Canine Angiopoietin 1 (ANGPT1) ELISA Kit-Sandwich
Sign In for Pricing
View Details 
A34005-Cy3 100 µg/Vial
Anti-SARS-CoV-2 NSP13/Helicase Antibody, Cy3 Conjugate
Sign In for Pricing
View Details MBS8420071-02 5x 1 Kit
Human Metalloproteinase Inhibitor 3 ELISA Kit
Sign In for Pricing
View Details