Biotin-PEG36-acid

Biotin-PEG36-acid, a PEG-based linker for PROTACs, connects two essential ligands, facilitating the formation of PROTAC molecules. This linker promotes selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O