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4E1rcat

Product Specifications

CAS Number

328998-25-0

Target

Autophagy, PERK

Related Pathways

Apoptosis, Autophagy

Purity

0.9947

Bioactivity

4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.

Smiles

OC(=O)c1ccc(cc1)N1C(=O)\C(=C\c2ccc(o2)-c2ccc(cc2)[N+]([O-])=O)C=C1c1ccccc1

Molecular Formula

C28H18N2O6

Molecular Weight

478.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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