9-Decyn-1-ol
Product Specifications
CAS Number
17643-36-6
Target
PROTAC Linker, Others
Related Pathways
Others, PROTAC
Bioactivity
9-Decyn-1-ol is an alkyl/ether-based PROTAC linker used in synthesizing PROTACs, acting as a conjugation agent to combine GDC-0068 and Lenalidomide to form INY-03-041. INY-03-041 is a potent and highly selective pan-Akt degrader that inhibits Akt1, Akt2, and Akt3 with IC50 values of 2.0 nM, 6.8 nM, and 3.5 nM, respectively[1].
Smiles
C(CCCC#C)CCCCO
Molecular Formula
C10H18O
Molecular Weight
154.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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