(-) -Indolactam V
Product Specifications
CAS Number
90365-57-4
Target
PKC
Related Pathways
Chromatin/Epigenetic|||Cytoskeletal Signaling
Bioactivity
(-) -Indolactam V, a potent PKC activator, exhibits binding affinities (Kis) of 3.36 nM and 1.03 ?M for ?-CRD2 and ?-CRD2, respectively, and dissociation constants (Kds) of 5.5 nM (?-C1B), 7.7 nM (?-C1B), 8.3 nM (?-C1B), 18.9 nM (?-C1A-long), 20.8 nM (?-C1A-long), 137 nM (?-C1B), 138 nM (?-C1A), and 213 nM (?-C1B), also demonstrating antitumor activity.
Smiles
CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23
Molecular Formula
C17H23N3O2
Molecular Weight
301.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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