YUKA1
Product Specifications
CAS Number
708991-09-7
Target
Histone Demethylase
Related Pathways
Chromatin/Epigenetic
Purity
0.9985
Bioactivity
YUKA1, a cell-permeable KDM5A inhibitor (IC50=2.66 μM) with a weak effect on KDM5C (IC50=7.12 μM) and no effect on other KDM isoforms, was able to increase the level of H3K4me3 in human cells and inhibit the proliferation of cancer cells, and also prevented the emergence of drug-resistant cells.
Smiles
S=C1NN=CN1NCC=2C=CC=C(OC)C2OCC=C
Molecular Formula
C13H16N4O2S
Molecular Weight
292.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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