YKL-05-099
Product Specifications
CAS Number
1936529-65-5
Target
SIK
Related Pathways
PI3K/Akt/mTOR signaling
Purity
0.9989
Bioactivity
YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. It can inhibit the activity of SIK1 (IC50: 10 nM) and SIK3 (IC50: 30 nM), and has a slightly weaker inhibitory effect on SIK2 (IC50: 40 nM) . [1]
Smiles
COc1ccc(nc1)N1C(=O)N(Cc2cnc(Nc3ccc(cc3OC)C3CCN(C)CC3)nc12)c1c(C)cccc1Cl
Molecular Formula
C32H34ClN7O3
Molecular Weight
600.11
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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