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XE 991 dihydrochloride

Product Specifications

CAS Number

122955-13-9

Target

Potassium Channel

Related Pathways

Membrane transporter/Ion channel

Purity

0.9896

Bioactivity

XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively) .

Smiles

Cl.Cl.O=C1c2ccccc2C(Cc2ccncc2)(Cc2ccncc2)c2ccccc12

Molecular Formula

C26H22Cl2N2O

Molecular Weight

449.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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