XE 991 dihydrochloride
Product Specifications
CAS Number
122955-13-9
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9896
Bioactivity
XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively) .
Smiles
Cl.Cl.O=C1c2ccccc2C(Cc2ccncc2)(Cc2ccncc2)c2ccccc12
Molecular Formula
C26H22Cl2N2O
Molecular Weight
449.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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