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WR99210 hydrochloride (47326-86-3 free base)

Product Specifications

CAS Number

30711-93-4

Target

Others, Parasite, DHFR

Related Pathways

Others, Metabolism, Microbiology/Virology, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

Purity

0.9996

Bioactivity

WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.

Smiles

NC1=NC(N)=NC(C)(C)N1OCCCOC2=CC(Cl)=C(Cl)C=C2Cl.[H]Cl

Molecular Formula

C14H19Cl4N5O2

Molecular Weight

431.14

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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