WR99210 hydrochloride (47326-86-3 free base)
Product Specifications
CAS Number
30711-93-4
Target
Others, Parasite, DHFR
Related Pathways
Others, Metabolism, Microbiology/Virology, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9996
Bioactivity
WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
Smiles
NC1=NC(N)=NC(C)(C)N1OCCCOC2=CC(Cl)=C(Cl)C=C2Cl.[H]Cl
Molecular Formula
C14H19Cl4N5O2
Molecular Weight
431.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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