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UPGL00004

Product Specifications

CAS Number

1890169-95-5

Target

Glutaminase

Related Pathways

Proteases/Proteasome

Purity

0.9793

Bioactivity

UPGL00004 is a potent glutaminase C (GAC) inhibitor with an IC50 of 29 nM. Kd of UPGL00004 for GAC was 27 nM. UPGL00004 has a strong inhibitory effect on the proliferation of highly aggressive triple negative breast cancer cell lines.

Smiles

O=C(Cc1ccccc1)Nc1nnc(NC2CCN(CC2)c2nnc(NC(=O)Cc3ccccc3)s2)s1

Molecular Formula

C25H26N8O2S2

Molecular Weight

534.66

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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