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UCL 2077

Product Specifications

CAS Number

918311-87-2

Target

Potassium Channel|||Others

Related Pathways

Membrane transporter/Ion channel|||Others

Purity

0.9958

Bioactivity

UCL 2077 is a subtype-selective blocker of the epilepsy-associated KCNQ channels and it also is a selective slow-afterhyperpolarization channel blocker, with IC50 of 500 nM in hippocampal neurons in culture, having minimal effects on Ca2+ channels, action potentials, input resistance, and the medium afterhyperpolarization.

Smiles

C(NCC=1C=CC=NC1)(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4

Molecular Formula

C25H22N2

Molecular Weight

350.46

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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