Bufalin
Product Specifications
CAS Number
465-21-4
Target
ATPase
Related Pathways
Membrane transporter/Ion channel
Purity
0.998
Bioactivity
Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic activity. Although the mechanism of action of bufalin is still under investigation, this agent is a specific Na+/K+-ATPase inhibitor and can induce apoptosis in Y cell lines through the activation of the transcription factor AP-1 via a mitogen activated protein kinase (MAPK) pathway.
Smiles
[H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@H](CC[C@]34O)c3ccc(=O)oc3)[C@@]1(C)CC[C@H](O)C2
Molecular Formula
C24H34O4
Molecular Weight
386.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VK681010-01 50 µg
InVivoMAb Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (RM2-01)
Sign In for Pricing
View Details VK681010-02 100 µg
InVivoMAb Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (RM2-01)
Sign In for Pricing
View Details VK681010-03 1 mg
InVivoMAb Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (RM2-01)
Sign In for Pricing
View Details MBS1579009-01 0.1 mg
Recombinant Mouse CD254/RANKL/TNFSF11 Protein, N-His-SUMO
Sign In for Pricing
View Details