TVB-3664
Product Specifications
CAS Number
2097262-58-1
Target
Fatty Acid Synthase
Related Pathways
Metabolism
Purity
0.9964
Bioactivity
TVB-3664 is an orally active, selective, reversible, and highly bioavailable fatty acid synthase inhibitor (FASN) with an IC50 for palmitate synthesis of 18 nM in human and 12 nM in mouse.Significantly inhibits microtubule protein palmitoylation and mRNA expression.
Smiles
COCc1nc([nH]c1-c1cc(C(=O)N2CC(C2)c2ccc(cc2)C#N)c(C)cc1C)C(F)(F)F
Molecular Formula
C25H23F3N4O2
Molecular Weight
468.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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