PF-06737007

1863905-38-7

Trk receptor

Tyrosine Kinase/Adaptors

PF-06737007 is an effective inhibitor of pan-Trk in cell-based assays (IC50s: 7.7 nM, 15 nM, and 3.9 nM for TrkA, TrkB, and TrkC, respectively) .

O(C1=C(C(N)=O)C=CC(OCC(C)(C)O)=C1)[C@@H]2[C@H](F)CN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)CC2

C25H28F4N2O6

528.49

Ice Packs

-20°C