Toyocamycin
Product Specifications
CAS Number
606-58-6
Target
IRE1, Apoptosis, Antifungal, CDK, Antibiotic
Related Pathways
Apoptosis, Microbiology/Virology, Cell Cycle/Checkpoint
Purity
0.9944
Bioactivity
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycetes, functioning as an XBP1 inhibitor and inhibiting IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM), and induces apoptosis.
Smiles
Nc1ncnc2n(cc(C#N)c12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Molecular Formula
C12H13N5O4
Molecular Weight
291.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C