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Toyocamycin

Product Specifications

CAS Number

606-58-6

Target

IRE1|||Apoptosis|||Antifungal|||CDK|||Antibiotic

Related Pathways

Apoptosis|||Microbiology/Virology|||Cell Cycle/Checkpoint

Purity

0.9944

Bioactivity

Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycetes, functioning as an XBP1 inhibitor and inhibiting IRE1?-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM), and induces apoptosis.

Smiles

Nc1ncnc2n(cc(C#N)c12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Molecular Formula

C12H13N5O4

Molecular Weight

291.26

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/A2CE2F34-2913-4893-A1BC-154DEF27C2C7/T17143

Available Sizes

Curated Selection

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