TIK-301
Product Specifications
CAS Number
118702-11-7
Target
5-HT Receptor, Melatonin Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM, respectively) . TIK-301 is also a 5-HT2B/5-HT2C receptor antagonist with antidepressant action. TIK-301 has the potential for sleep disorders and other circadian rhythm disorders treatment.
Smiles
[C@@H](CNC(C)=O)(C)C=1C=2C(NC1)=CC(Cl)=C(OC)C2
Molecular Formula
C14H17ClN2O2
Molecular Weight
280.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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