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TIK-301

Product Specifications

CAS Number

118702-11-7

Target

5-HT Receptor, Melatonin Receptor

Related Pathways

GPCR/G Protein, Neuroscience

Bioactivity

TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM, respectively) . TIK-301 is also a 5-HT2B/5-HT2C receptor antagonist with antidepressant action. TIK-301 has the potential for sleep disorders and other circadian rhythm disorders treatment.

Smiles

[C@@H](CNC(C)=O)(C)C=1C=2C(NC1)=CC(Cl)=C(OC)C2

Molecular Formula

C14H17ClN2O2

Molecular Weight

280.75

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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