Umbralisib hydrochloride
Product Specifications
CAS Number
1532533-78-0
Target
PI3K, Casein Kinase
Related Pathways
Metabolism, Stem Cells, PI3K/Akt/mTOR signaling
Bioactivity
Umbralisib hydrochloride is a novel PI3Kδ inhibitor (IC50 and EC50 of 22.2 nM and 24.3 nM, respectively) . Umbralisib hydrochloride is also active against CK1ε (EC50: 6.0 μM) .
Smiles
Cl.CC(C)Oc1ccc(cc1F)-c1nn([C@@H](C)c2oc3ccc(F)cc3c(=O)c2-c2cccc(F)c2)c2ncnc(N)c12
Molecular Formula
C31H25ClF3N5O3
Molecular Weight
608.01
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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