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Boc-Val-Ala-PAB-PNP

Product Specifications

UNSPSC Description

Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Target Antigen

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-val-ala-pab-pnp.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

CC([C@H](NC(OC(C)(C)C)=O)C(N[C@H](C(NC1=CC=C(C=C1)COC(OC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)C)=O)C

Molecular Weight

558.58

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-130932/Boc-Val-Ala-PAB-PNP-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-130932/Boc-Val-Ala-PAB-PNP-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1884578-00-0

Available Sizes

Curated Selection

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