Tefinostat
Product Specifications
CAS Number
914382-60-8
Target
Apoptosis, HDAC
Related Pathways
Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair
Purity
0.9983
Bioactivity
Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor that is cleaved to the active acid CHR-2847 by intracellular esterase human carboxylesterase-1 (hCE-1) . Tefinostat exhibits antitumor activity and can be used in the study of leukemia and advanced hematologic malignancies.
Smiles
ONC(=O)CCCCCCC(=O)Nc1ccc(CN[C@H](C(=O)OC2CCCC2)c2ccccc2)cc1
Molecular Formula
C28H37N3O5
Molecular Weight
495.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
T9901A-729-01 1 mg
Human IgG1 (K214R/E356D/M358L) -kappa Isotype control
Sign In for Pricing
View Details T9901A-729-02 5 mg
Human IgG1 (K214R/E356D/M358L) -kappa Isotype control
Sign In for Pricing
View Details T9901A-729-03 25 mg
Human IgG1 (K214R/E356D/M358L) -kappa Isotype control
Sign In for Pricing
View Details T9901A-729-04 50 mg
Human IgG1 (K214R/E356D/M358L) -kappa Isotype control
Sign In for Pricing
View Details T9901A-729-05 100 mg
Human IgG1 (K214R/E356D/M358L) -kappa Isotype control
Sign In for Pricing
View Details