TAS6417
Product Specifications
CAS Number
1661854-97-2
Target
Apoptosis, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Apoptosis
Purity
0.9971
Bioactivity
Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor that uniquely binds to the ATP binding site of the EGFR hinge region with an IC50 value of 1.1-8.0 nM.
Smiles
CC1=C[C@@H](Cn2c1c(-c1cnc3ccccc3c1)c1c(N)ncnc21)NC(=O)C=C
Molecular Formula
C23H20N6O
Molecular Weight
396.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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