TAS05567
Product Specifications
CAS Number
1429038-15-2
Target
JAK, c-RET, FLT, Syk
Related Pathways
Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, Stem Cells, JAK/STAT signaling
Bioactivity
TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM), showing >70% inhibition of Syk and four other kinases [FLT3 (IC50: 10 nM), JAK2 (IC50: 4.8 nM), KDR (IC50: 600 nM), RET (IC50: 29 nM) ] in a panel of 192 kinases.
Smiles
CC=1C=2C(=CN(C(C)(C)C)N2)C=C(NC=3C(C(N)=O)=NN=C(N[C@H]4[C@@H](N)COCC4)N3)C1
Molecular Formula
C21H29N9O2
Molecular Weight
439.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
IMSARTPRENPSG2C6C100UG 100 µg
Mouse Anti Rat Prorenin Prosegment Monoclonal Clone 2C6 100ug
Sign In for Pricing
View Details 
MBS2053332-01 0.1 mL
APC-Linked Polyclonal Antibody to Glucagon (GC)
Sign In for Pricing
View Details MBS2053332-02 0.2 mL
APC-Linked Polyclonal Antibody to Glucagon (GC)
Sign In for Pricing
View Details MBS2053332-03 0.5 mL
APC-Linked Polyclonal Antibody to Glucagon (GC)
Sign In for Pricing
View Details