TAK-243
Product Specifications
CAS Number
1450833-55-2
Target
NF-κB, Apoptosis, E1/E2/E3 Enzyme
Related Pathways
Apoptosis, NF-κB, Ubiquitination
Purity
0.9893
Bioactivity
TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM), blocking ubiquitin binding and disrupting both mono-ubiquitin signaling and overall protein ubiquitination. TAK-243 exhibits antitumor activity and promotes apoptosis.
Smiles
NS(=O)(=O)OC[C@H]1C[C@@H](Nc2ccnc3cc(nn23)-c2cccc(SC(F)(F)F)c2)[C@H](O)[C@@H]1O
Molecular Formula
C19H20F3N5O5S2
Molecular Weight
519.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PB9778-carrier-free 100 µg/Vial
Anti-Phospholipase A2/PLA2G4A Antibody Picoband® (Carrier-free Conjugate)
Sign In for Pricing
View Details