SAG-d3
SAG-d3 is deuterium labeled SAG. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM) [1].
Product Specifications
UNSPSC
12352005
Target
Smo
Type
Isotope-Labeled Compounds
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=C(SC2=CC=CC=C21)C(N(CC3=CC=CC(C4=CC=NC=C4)=C3)[C@H]5CC[C@@H](CC5)NC([2H])([2H])[2H])=O
Molecular Formula
C28H25D3ClN3OS
Molecular Weight
493.08
References & Citations
[1]Chen JK, et al. Small molecule modulation of Smoothened activity. Proc Natl Acad Sci U S A. 2002 Oct 29;99 (22) :14071-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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