TAK-220
Product Specifications
CAS Number
333994-00-6
Target
CCR, HIV Protease
Related Pathways
Immunology/Inflammation, Proteases/Proteasome, Microbiology/Virology, GPCR/G Protein
Bioactivity
TAK-220 is a selective and orally bioavailable CCR5 antagonist with IC50 values of 3.5 nM for RANTES binding inhibition and 1.4 nM for MIP-1α binding inhibition to CCR5.
Smiles
CC(=O)N1CCC(CC1)C(=O)N(CCCN1CCC(Cc2ccc(cc2)C(N)=O)CC1)c1ccc(C)c(Cl)c1
Molecular Formula
C31H41ClN4O3
Molecular Weight
553.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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