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TAK-220

Product Specifications

CAS Number

333994-00-6

Target

CCR|||HIV Protease

Related Pathways

Immunology/Inflammation|||Proteases/Proteasome|||Microbiology/Virology|||GPCR/G Protein

Bioactivity

TAK-220 is a selective and orally bioavailable CCR5 antagonist with IC50 values of 3.5 nM for RANTES binding inhibition and 1.4 nM for MIP-1? binding inhibition to CCR5.

Smiles

CC(=O)N1CCC(CC1)C(=O)N(CCCN1CCC(Cc2ccc(cc2)C(N)=O)CC1)c1ccc(C)c(Cl)c1

Molecular Formula

C31H41ClN4O3

Molecular Weight

553.14

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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