SU16f
Product Specifications
CAS Number
251356-45-3
Target
PDGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9838
Bioactivity
SU16f (3-substituted indolin-2-one 16f) is a potent and selective PDGFRβ inhibitor (IC50s: 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively) . Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs conditioned medium in gastric cancer cell proliferation and migration.
Smiles
C(=C1C=2C(=CC(=CC2)C3=CC=CC=C3)NC1=O)C4=C(C)C(CCC(O)=O)=C(C)N4
Molecular Formula
C24H22N2O3
Molecular Weight
386.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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