Streptonigrin
Product Specifications
CAS Number
3930-19-6
Target
Others|||PAD|||MDM-2/p53|||HIF/HIF Prolyl-Hydroxylase|||Apoptosis|||E1/E2/E3 Enzyme|||Antibiotic
Related Pathways
Chromatin/Epigenetic|||Apoptosis|||Microbiology/Virology|||Metabolism|||Others|||Ubiquitination
Bioactivity
Streptonigrin is a natural product produced by Streptomyces flocculus, has both anti-tumor and anti-bacterial activity. Streptonigrin acts as a pan-PAD inhibitor (IC50s: 48.3±34.2 ?M, 26.1±0.3 ?M, 0.43±0.03 ?M, and 2.5±0.4 ?M for PAD1, PAD2, PAD3, and PAD4, respectively) .
Smiles
COC1=C(N)C(=O)c2nc(ccc2C1=O)-c1nc(C(O)=O)c(C)c(c1N)-c1ccc(OC)c(OC)c1O
Molecular Formula
C25H22N4O8
Molecular Weight
506.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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