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SPR inhibitor 3

Product Specifications

CAS Number

1292285-54-1

Target

Others

Related Pathways

Others

Bioactivity

SPR inhibitor 3 is an effective sepiapterin reductase inhibitor. SPR inhibitor 3 decreases neuropathic and inflammatory pain through a reduction of BH4 levels. SPR inhibitor 3 shows a high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM) .

Smiles

COCC(=O)NCCc1c(C)[nH]c2ccc(O)cc12

Molecular Formula

C14H18N2O3

Molecular Weight

262.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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