SNIPER (BRD) -1

SNIPER (BRD) -1 is a chemical compound composed of a derivative of the IAP antagonist LCL-161 and the BET inhibitor (+) -JQ-1, linked together. It promotes the degradation of BRD4 through the ubiquitin-proteasome pathway and effectively degrades cIAP1, cIAP2, and XIAP with IC50 values of 6.8 nM, 17 nM, and 49nM, respectively[1].

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