SF1126
Product Specifications
CAS Number
936487-67-1
Target
Apoptosis, Others, PI3K
Related Pathways
Apoptosis, Others, PI3K/Akt/mTOR signaling
Bioactivity
SF1126 is a relevant pan and dual first-in-class PI3K/BRD4 inhibitor. An RGDS-conjugated LY294002 prodrug, it is designed for increased solubility and specifically binds to integrins within the tumor compartment.
Smiles
C(OC(CCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(O)=O)CO)=O)CC([O-])=O)=O)=O)CCCNC(=N)N)=O)=O)[N+]1(CCOCC1)C=2OC3=C(C=CC=C3C(=O)C2)C4=CC=CC=C4
Molecular Formula
C39H48N8O14
Molecular Weight
852.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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