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SB-267268

Product Specifications

CAS Number

205678-26-8

Target

Others, Integrin

Related Pathways

Cytoskeletal Signaling, Others

Bioactivity

SB-267268 inhibits human and mouse αvβ3 (IC50s: 0.68 and 0.29 nM, respectively) . SB-267268 is a selective and nonpeptidic alpha (v) beta3 and alpha (v) beta5 integrins antagonist (Kis: 0.9, 0.5 and 0.7 nM for human αvβ3, monkey αvβ3 and human αvβ5, respectively) .

Smiles

C(C(F)(F)F)N1CC=2C(C[C@@H](CC(O)=O)C1=O)=CC=C(OCCCNC3=CC=CC=N3)C2

Molecular Formula

C22H24F3N3O4

Molecular Weight

451.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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