SB-267268
Product Specifications
CAS Number
205678-26-8
Target
Others, Integrin
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
SB-267268 inhibits human and mouse αvβ3 (IC50s: 0.68 and 0.29 nM, respectively) . SB-267268 is a selective and nonpeptidic alpha (v) beta3 and alpha (v) beta5 integrins antagonist (Kis: 0.9, 0.5 and 0.7 nM for human αvβ3, monkey αvβ3 and human αvβ5, respectively) .
Smiles
C(C(F)(F)F)N1CC=2C(C[C@@H](CC(O)=O)C1=O)=CC=C(OCCCNC3=CC=CC=N3)C2
Molecular Formula
C22H24F3N3O4
Molecular Weight
451.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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